Construct · 1 fields · 1 citations

global epistasis: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

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Evolutionary genetics

a pattern in which a mutation's fitness effect depends mainly on the background's overall fitness, making adaptation predictable.

In evolutionary genetics, global epistasis refers to a pattern in which a mutation's fitness effect depends mainly on the background's overall fitness, making adaptation predictable. This meaning comes from Kryazhimskiy (2014) in Science.[1]

Unit
Recovery means
Measured by

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Nearby constructs

adaptation5 fields · 7 citationsjingle · one word, five constructs epistasis1 fields · 1 citationsanchor · a standalone construct fitness4 fields · 5 citationsjingle · one word, four constructs

References

Kryazhimskiy, S., Rice, D. P., Jerison, E. R., & Desai, M. M. (2014). Global epistasis makes adaptation predictable despite sequence-level stochasticity. Science, 344(6191), 1519-1522. https://doi.org/10.1126/science.1250939

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