Construct · 1 fields · 1 citations

ground state pluripotency: a standalone construct

One name. One construct. A landmark on the map.

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Stem cell biology

the proposal that embryonic stem cells self-renew on their own once differentiation-inducing signals are blocked, needing no extrinsic instruction.

In stem cell biology, ground state pluripotency refers to the proposal that embryonic stem cells self-renew on their own once differentiation-inducing signals are blocked, needing no extrinsic instruction. This meaning comes from Ying (2008) in Nature.[1]

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructs ground4 fields · 7 citationsjingle · one word, four constructs state4 fields · 6 citationsjingle · one word, four constructs

References

Ying, Q., Wray, J., Nichols, J., Batlle-Morera, L., Doble, B., Woodgett, J., Cohen, P., & Smith, A. (2008). The ground state of embryonic stem cell self-renewal. Nature, 453(7194), 519-523. https://doi.org/10.1038/nature06968

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