Construct · 1 fields · 1 citations

high-dose hook effect: a standalone construct

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Clinical laboratory science

falsely low results in one-step sandwich immunoassays when very high analyte levels saturate both antibodies.

In clinical laboratory science, high-dose hook effect refers to falsely low results in one-step sandwich immunoassays when very high analyte levels saturate both antibodies. This meaning comes from Amarasiri Fernando (1992) in Journal of Immunological Methods.[1]

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Recovery means
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Nearby constructs

hook2 fields · 2 citationsjingle · one word, two constructs scaffold prozone effect1 fields · 1 citationsanchor · a standalone construct

References

Amarasiri Fernando, S., & Wilson, G. S. (1992). Studies of the ‘hook’ effect in the one-step sandwich immunoassay. Journal of Immunological Methods, 151(1-2), 47-66. https://doi.org/10.1016/0022-1759(92)90104-2

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