Construct · 1 fields · 1 citations

higher-order epistasis: a standalone construct

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Evolutionary genetics

interactions among three or more mutations that are not explained by their pairwise interactions.

In evolutionary genetics, higher-order epistasis refers to interactions among three or more mutations that are not explained by their pairwise interactions. This meaning comes from Weinreich (2013) in Current Opinion in Genetics & Development.[1]

Unit
Recovery means
Measured by

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Nearby constructs

current3 fields · 6 citationsjingle · one word, three constructs development1 fields · 2 citationsanchor · a standalone construct epistasis1 fields · 1 citationsanchor · a standalone construct

References

Weinreich, D. M., Lan, Y., Wylie, C. S., & Heckendorn, R. B. (2013). Should evolutionary geneticists worry about higher-order epistasis? Current Opinion in Genetics & Development, 23(6), 700-707. https://doi.org/10.1016/j.gde.2013.10.007

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