Construct · 1 fields · 1 citations

immune activation hypothesis of HIV: a standalone construct

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Infectious diseases

the proposal that chronic generalized immune activation, more than direct viral killing, drives CD4 T cell loss and progression in HIV.

In infectious diseases, immune activation hypothesis of HIV refers to the proposal that chronic generalized immune activation, more than direct viral killing, drives CD4 T cell loss and progression in HIV. This meaning comes from Grossman (2006) in Nature Medicine.[1]

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activation4 fields · 4 citationsjingle · one word, four constructs cell2 fields · 3 citationsjingle · one word, two constructs hypothesis2 fields · 2 citationsjingle · one word, two constructs

References

Grossman, Z., Meier-Schellersheim, M., Paul, W. E., & Picker, L. J. (2006). Pathogenesis of HIV infection: what the virus spares is as important as what it destroys. Nature Medicine, 12(3), 289-295. https://doi.org/10.1038/nm1380

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