Construct · 1 fields · 1 citations

initiation-promotion model: a standalone construct

One name. One construct. A landmark on the map.

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Genetic toxicology

the model in which skin cancer arises after an initiating carcinogen followed by repeated exposure to a promoting agent.

In genetic toxicology, initiation-promotion model refers to the model in which skin cancer arises after an initiating carcinogen followed by repeated exposure to a promoting agent. This meaning comes from Berenblum (1947) in British Journal of Cancer.[1]

Unit
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Nearby constructs

promotion2 fields · 2 citationsjingle · one word, two constructs agent3 fields · 5 citationsjingle · one word, three constructs exposure6 fields · 13 citationsjingle · one name, six constructs

References

Berenblum, I., & Shubik, P. (1947). A New, Quantitative, Approach to the Study of the Stages of Chemical Carcinogenesis in the Mouse's Skin. British Journal of Cancer, 1(4), 383-391. https://doi.org/10.1038/bjc.1947.36

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