Construct · 1 fields · 1 citations

interim analysis: a standalone construct

One name. One construct. A landmark on the map.

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interimanalysis1 CONSTRUCTInterim analysisO'BRIEN · CLINICAL RESEARCH

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Clinical research methods

looking at trial data before planned completion, with stopping boundaries that keep the overall error rate controlled.

In clinical research methods, interim analysis refers to looking at trial data before planned completion, with stopping boundaries that keep the overall error rate controlled. This meaning comes from O'Brien (1979) in Biometrics.[1]

Unit
Recovery means
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Nearby constructs

error4 fields · 8 citationsjingle · one word, four constructsPocock boundary1 fields · 1 citationsanchor · a standalone constructseamless phase II/III design1 fields · 1 citationsanchor · a standalone construct

References

  1. O'Brien, P. C., & Fleming, T. R. (1979). A Multiple Testing Procedure for Clinical Trials. Biometrics, 35(3), 549. https://doi.org/10.2307/2530245

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