Construct · 1 fields · 1 citations

LD score regression: a standalone construct

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Genomics

a method that regresses association statistics on linkage disequilibrium scores to separate true polygenic signal from confounding.

In genomics, LD score regression refers to a method that regresses association statistics on linkage disequilibrium scores to separate true polygenic signal from confounding. This meaning comes from Bulik-Sullivan (2015) in Nature Genetics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

association4 fields · 4 citationsjingle · one word, four constructs linkage disequilibrium1 fields · 1 citationsanchor · a standalone construct linkage4 fields · 6 citationsjingle · one word, four constructs

References

Bulik-Sullivan, B. K., Loh, P. R., Finucane, H. K., Ripke, S., Yang, J., Patterson, N., Daly, M. J., Price, A. L., & Neale, B. M. (2015). LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nature Genetics, 47(3), 291-295. https://doi.org/10.1038/ng.3211

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