Construct · 1 fields · 1 citations

ligand efficiency: a standalone construct

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Pharmacology

binding energy of a compound divided by its number of heavy atoms, used to compare leads of different sizes.

In pharmacology, ligand efficiency refers to binding energy of a compound divided by its number of heavy atoms, used to compare leads of different sizes. This meaning comes from Hopkins (2004) in Drug Discovery Today.[1]

Unit
Recovery means
Measured by

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Nearby constructs

binding efficiency index1 fields · 1 citationsanchor · a standalone construct binding4 fields · 4 citationsjingle · one word, four constructs compound3 fields · 3 citationsjingle · one word, three constructs

References

Hopkins, A. L., Groom, C. R., & Alex, A. (2004). Ligand efficiency: a useful metric for lead selection. Drug Discovery Today, 9(10), 430-431. https://doi.org/10.1016/s1359-6446(04)03069-7

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