Construct · 1 fields · 1 citations

binding efficiency index: a standalone construct

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Medicinal chemistry

potency per unit molecular mass, proposed with a polar-surface version as coordinates for tracking ligand efficiency during optimization.

In medicinal chemistry, binding efficiency index refers to potency per unit molecular mass, proposed with a polar-surface version as coordinates for tracking ligand efficiency during optimization. This meaning comes from Abad-Zapatero (2005) in Drug Discovery Today.[1]

Unit
Recovery means
Measured by

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Nearby constructs

binding4 fields · 4 citationsjingle · one word, four constructs efficiency4 fields · 5 citationsjingle · one word, four constructs index5 fields · 11 citationsjingle · one word, five constructs

References

Abad-Zapatero, C., & Metz, J. T. (2005). Ligand efficiency indices as guideposts for drug discovery. Drug Discovery Today, 10(7), 464-469. https://doi.org/10.1016/s1359-6446(05)03386-6

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