Construct · 1 fields · 1 citations

lineage infidelity: a standalone construct

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Stem cell biology

the transient coexpression of fate programs from different lineages by stem cells under stress such as wounding, a state that persists in cancer.

In stem cell biology, lineage infidelity refers to the transient coexpression of fate programs from different lineages by stem cells under stress such as wounding, a state that persists in cancer. This meaning comes from Ge (2017) in Cell.[1]

Unit
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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructs lineage3 fields · 7 citationsjingle · one word, three constructs state4 fields · 6 citationsjingle · one word, four constructs

References

Ge, Y., Gomez, N. C., Adam, R. C., Nikolova, M., Yang, H., Verma, A., Lu, C. P., Polak, L., Yuan, S., Elemento, O., & Fuchs, E. (2017). Stem Cell Lineage Infidelity Drives Wound Repair and Cancer. Cell, 169(4), 636-650.e14. https://doi.org/10.1016/j.cell.2017.03.042

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