Construct · 1 fields · 1 citations

lipophilic efficiency: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Medicinal chemistry

potency of a compound minus its lipophilicity, used to judge whether gains in activity come from specific binding rather than added greasiness.

In medicinal chemistry, lipophilic efficiency refers to potency of a compound minus its lipophilicity, used to judge whether gains in activity come from specific binding rather than added greasiness. This meaning comes from Leeson (2007) in Nature Reviews Drug Discovery.[1]

Unit
Recovery means
Measured by

Run it through the Collider, or take the citations with you.

See how lipophilic efficiency sits against neighbouring constructs in the Collider, or export every reference on this page in one click.

Open in Collider Export BibTeX Report this entry

Nearby constructs

binding4 fields · 4 citationsjingle · one word, four constructs compound3 fields · 3 citationsjingle · one word, three constructs efficiency4 fields · 5 citationsjingle · one word, four constructs

References

Leeson, P. D., & Springthorpe, B. (2007). The influence of drug-like concepts on decision-making in medicinal chemistry. Nature Reviews Drug Discovery, 6(11), 881-890. https://doi.org/10.1038/nrd2445

Cited on this page?

Confirm your construct, or correct us.

If your work is cited behind one of these entries, you know better than we do whether we captured the meaning right. Confirm it, suggest an edit, or dispute it, and your name goes on the entry as an author who has checked it, linked to your ORCID.

Claim your construct