Construct · 1 fields · 1 citations

loop extrusion: a standalone construct

One name. One construct. A landmark on the map.

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Genomics

proposed mechanism where a motor complex reels DNA into a growing loop until it meets boundary elements.

In genomics, loop extrusion refers to proposed mechanism where a motor complex reels DNA into a growing loop until it meets boundary elements. This meaning comes from Fudenberg (2016) in Cell Reports.[1]

Unit
Recovery means
Measured by

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Nearby constructs

boundary4 fields · 4 citationsjingle · one word, four constructs cell2 fields · 3 citationsjingle · one word, two constructs complex4 fields · 4 citationsjingle · one word, four constructs

References

Fudenberg, G., Imakaev, M., Lu, C., Goloborodko, A., Abdennur, N., & Mirny, L. A. (2016). Formation of Chromosomal Domains by Loop Extrusion. Cell Reports, 15(9), 2038-2049. https://doi.org/10.1016/j.celrep.2016.04.085

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