Construct · 1 fields · 1 citations

lowest-observed-adverse-effect level: a standalone construct

One name. One construct. A landmark on the map.

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lowest-observed-adverse-effectlevel1 CONSTRUCTRisk assessmentDORATO · RISK ASSESSMENT

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Risk assessment

the lowest tested dose at which a biologically significant adverse effect is seen compared with controls.

In risk assessment, lowest-observed-adverse-effect level refers to the lowest tested dose at which a biologically significant adverse effect is seen compared with controls. This meaning comes from Dorato (2005) in Regulatory Toxicology and Pharmacology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

no-observed-adverse-effect level1 fields · 1 citationsanchor · a standalone constructthreshold5 fields · 6 citationsjingle · one word, five constructsdose3 fields · 3 citationsinvariant · one construct, three systems

References

  1. Dorato, M. A., & Engelhardt, J. A. (2005). The no-observed-adverse-effect-level in drug safety evaluations: Use, issues, and definition(s). Regulatory Toxicology and Pharmacology, 42(3), 265-274. https://doi.org/10.1016/j.yrtph.2005.05.004

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