Construct · 1 fields · 1 citations

Manchester scoring system: a standalone construct

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Medical genetics

a family-history scoring system that estimates the chance of finding a BRCA1 or BRCA2 pathogenic variant in a family.

In medical genetics, Manchester scoring system refers to a family-history scoring system that estimates the chance of finding a BRCA1 or BRCA2 pathogenic variant in a family. This meaning comes from Evans (2004) in Journal of Medical Genetics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

chance4 fields · 6 citationsjingle · one word, four constructs family3 fields · 3 citationsjingle · one word, three constructs variant3 fields · 5 citationsjingle · one word, three constructs

References

Evans, D. G. R., Eccles, D. M., Rahman, N., Young, K., Bulman, M., Amir, E., Shenton, A., Howell, A., & Lalloo, F. (2004). A new scoring system for the chances of identifying a BRCA1/2 mutation outperforms existing models including BRCAPRO. Journal of Medical Genetics, 41(6), 474-480. https://doi.org/10.1136/jmg.2003.017996

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