Construct · 1 fields · 1 citations

margin of exposure: a standalone construct

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Risk assessment

the ratio between a reference point on the dose-response curve and the estimated human exposure, used to prioritize genotoxic carcinogens.

In risk assessment, margin of exposure refers to the ratio between a reference point on the dose-response curve and the estimated human exposure, used to prioritize genotoxic carcinogens. This meaning comes from Barlow (2006) in Food and Chemical Toxicology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

exposure6 fields · 13 citationsjingle · one name, six constructs margin2 fields · 2 citationsjingle · one word, two constructs reference3 fields · 3 citationsjingle · one word, three constructs

References

Barlow, S., Renwick, A. G., Kleiner, J., Bridges, J. W., Busk, L., Dybing, E., Edler, L., Eisenbrand, G., Fink-Gremmels, J., Knaap, A., Kroes, R., Liem, D., Müller, D. J. G., Page, S., Rolland, V., Schlatter, J., Tritscher, A., Tueting, W., & Würtzen, G. (2006). Risk assessment of substances that are both genotoxic and carcinogenic. Food and Chemical Toxicology, 44(10), 1636-1650. https://doi.org/10.1016/j.fct.2006.06.020

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