Construct · 1 fields · 1 citations

metabolic activation: a standalone construct

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Toxicology

conversion of a chemical by body enzymes into reactive electrophilic metabolites that bind DNA and protein, the ultimate carcinogens.

In toxicology, metabolic activation refers to conversion of a chemical by body enzymes into reactive electrophilic metabolites that bind DNA and protein, the ultimate carcinogens. This meaning comes from Miller (1981) in Cancer.[1]

Unit
Recovery means
Measured by

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Nearby constructs

activation4 fields · 4 citationsjingle · one word, four constructs body2 fields · 3 citationsjingle · one word, two constructs conversion5 fields · 5 citationsjingle · one word, four turnings

References

Miller, E. C., & Miller, J. A. (1981). Searches for ultimate chemical carcinogens and their reactions with cellular macromolecules. Cancer, 47(10), 2327-2345. https://doi.org/10.1002/1097-0142(19810515)47:10<2327::aid-cncr2820471003>3.0.co;2-z

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