Construct · 1 fields · 1 citations

mitochondrial bottleneck: a standalone construct

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Genetics

the sharp drop in mitochondrial DNA copies passed through the germline, which lets heteroplasmy levels shift quickly between generations.

In genetics, mitochondrial bottleneck refers to the sharp drop in mitochondrial DNA copies passed through the germline, which lets heteroplasmy levels shift quickly between generations. This meaning comes from Cree (2008) in Nature Genetics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

bottleneck4 fields · 5 citationsjingle · one word, four constructs shift4 fields · 7 citationsjingle · one word, four constructs

References

Cree, L. M., Samuels, D. C., de Sousa Lopes, S. C., Rajasimha, H. K., Wonnapinij, P., Mann, J. R., Dahl, H. M., & Chinnery, P. F. (2008). A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes. Nature Genetics, 40(2), 249-254. https://doi.org/10.1038/ng.2007.63

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