Construct · 1 fields · 1 citations

mitochondrial threshold effect: a standalone construct

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mitochondrialthreshold effect1 CONSTRUCTMitochondrial thresholdROSSIGNOL · MEDICAL GENETICS

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Medical genetics

the pattern in which a mitochondrial defect shows up only after the share of mutant mitochondrial DNA or the loss of function passes a critical level.

In medical genetics, mitochondrial threshold effect refers to the pattern in which a mitochondrial defect shows up only after the share of mutant mitochondrial DNA or the loss of function passes a critical level. This meaning comes from Rossignol (2003) in Biochemical Journal.[1]

Unit
Recovery means
Measured by

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Nearby constructs

critical level1 fields · 1 citationsanchor · a standalone constructdefect4 fields · 7 citationsjingle · one word, four constructsfunction5 fields · 6 citationsjingle · one word, five constructs

References

  1. Rossignol, R., Faustin, B., Rocher, C., Malgat, M., Mazat, J., & Letellier, T. (2003). Mitochondrial threshold effects. Biochemical Journal, 370(3), 751-762. https://doi.org/10.1042/bj20021594

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