Construct · 1 fields · 1 citations

molecular initiating event: a standalone construct

One name. One construct. A landmark on the map.

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molecularinitiating event1 CONSTRUCTMolecular initiatingANKLEY · TOXICOLOGY

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Toxicology

the first interaction between a chemical and a biological molecule, such as receptor binding, that starts an adverse outcome pathway.

In toxicology, molecular initiating event refers to the first interaction between a chemical and a biological molecule, such as receptor binding, that starts an adverse outcome pathway. This meaning comes from Ankley (2009) in Environmental Toxicology and Chemistry.[1]

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Nearby constructs

adverse outcome pathway1 fields · 1 citationsanchor · a standalone constructbinding4 fields · 4 citationsjingle · one word, four constructsevent3 fields · 5 citationsjingle · one word, three constructs

References

  1. Ankley, G. T., Bennett, R. S., Erickson, R. J., Hoff, D. J., Hornung, M. W., Johnson, R. D., Mount, D. R., Nichols, J. W., Russom, C. L., Schmieder, P. K., Serrano, J. A., Tietge, J. E., & Villeneuve, D. L. (2009). Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment. Environmental Toxicology and Chemistry, 29(3), 730-741. https://doi.org/10.1002/etc.34

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