Construct · 1 fields · 1 citations

mutational signature: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

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Cancer biology

characteristic patterns of somatic mutations left in tumor genomes by specific processes such as tobacco exposure or defective repair.

In cancer biology, mutational signature refers to characteristic patterns of somatic mutations left in tumor genomes by specific processes such as tobacco exposure or defective repair. This meaning comes from Alexandrov (2013) in Nature.[1]

Unit
Recovery means
Measured by

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Nearby constructs

exposure6 fields · 13 citationsjingle · one name, six constructs signature3 fields · 4 citationsjingle · one word, three constructs

References

Alexandrov, L. B., Nik-Zainal, S., Wedge, D. C., Aparicio, S. A., Behjati, S., Biankin, A. V., Bignell, G. R., Bolli, N., Borg, A., Børresen-Dale, A. L., Boyault, S., Burkhardt, B., Butler, A. P., Caldas, C., Davies, H. R., Desmedt, C., Eils, R., Eyfjörd, J. E., Foekens, J. A., ... Stratton, M. R. (2013). Signatures of mutational processes in human cancer. Nature, 500(7463), 415-421. https://doi.org/10.1038/nature12477

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