Construct · 1 fields · 1 citations

mutator phenotype hypothesis: a standalone construct

One name. One construct. A landmark on the map.

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mutator phenotypehypothesis1 CONSTRUCTMutator phenotypeLOEB · CANCER BIOLOGY

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Cancer biology

the proposal that tumors carry raised mutation rates early on, which explains how they gather the many mutations cancer needs.

In cancer biology, mutator phenotype hypothesis refers to the proposal that tumors carry raised mutation rates early on, which explains how they gather the many mutations cancer needs. This meaning comes from Loeb (2011) in Nature Reviews Cancer.[1]

Unit
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Measured by

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Nearby constructs

carry1 fields · 1 citationsanchor · a standalone constructhypothesis2 fields · 2 citationsjingle · one word, two constructsmutation4 fields · 4 citationsjingle · one word, four constructs

References

  1. Loeb, L. A. (2011). Human cancers express mutator phenotypes: origin, consequences and targeting. Nature Reviews Cancer, 11(6), 450-457. https://doi.org/10.1038/nrc3063

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