Construct · 1 fields · 1 citations

neutral drift of stem cells: a standalone construct

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neutral driftof stem cells1 CONSTRUCTNeutral drift of stemLOPEZ-GARCIA · STEM CELL

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Stem cell biology

the pattern in which equally potent stem cells are randomly lost and replaced, so clones drift toward monoclonality with no clone having an advantage.

In stem cell biology, neutral drift of stem cells refers to the pattern in which equally potent stem cells are randomly lost and replaced, so clones drift toward monoclonality with no clone having an advantage. This meaning comes from Lopez-Garcia (2010) in Science.[1]

Unit
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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructsclone3 fields · 3 citationsjingle · one word, three constructsdrift5 fields · 6 citationsjingle · one word, five constructs

References

  1. Lopez-Garcia, C., Klein, A. M., Simons, B. D., & Winton, D. J. (2010). Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift. Science, 330(6005), 822-825. https://doi.org/10.1126/science.1196236

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