Construct · 1 fields · 1 citations

Norton-Simon hypothesis: a standalone construct

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Oncology

the proposal that chemotherapy kills tumor cells in proportion to the tumor's growth rate under Gompertzian kinetics, which motivates dose-dense scheduling.

In oncology, Norton-Simon hypothesis refers to the proposal that chemotherapy kills tumor cells in proportion to the tumor's growth rate under Gompertzian kinetics, which motivates dose-dense scheduling. This meaning comes from Simon (2006) in Nature Clinical Practice Oncology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

growth4 fields · 4 citationsjingle · one word, four constructs hypothesis2 fields · 2 citationsjingle · one word, two constructs practice3 fields · 4 citationsjingle · one word, three constructs

References

Simon, R., & Norton, L. (2006). The Norton–Simon hypothesis: designing more effective and less toxic chemotherapeutic regimens. Nature Clinical Practice Oncology, 3(8), 406-407. https://doi.org/10.1038/ncponc0560

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