Construct · 1 fields · 1 citations

oncogenic shock: a standalone construct

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Oncology

the proposal that inhibiting an addicting oncogene causes survival signals to decay faster than death signals, tipping cancer cells toward apoptosis.

In oncology, oncogenic shock refers to the proposal that inhibiting an addicting oncogene causes survival signals to decay faster than death signals, tipping cancer cells toward apoptosis. This meaning comes from Sharma (2006) in Cancer Cell.[1]

Unit
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Nearby constructs

apoptosis1 fields · 3 citationsanchor · a standalone construct cell2 fields · 3 citationsjingle · one word, two constructs decay4 fields · 5 citationsjingle · one word, four constructs

References

Sharma, S. V., Gajowniczek, P., Way, I. P., Lee, D. Y., Jiang, J., Yuza, Y., Classon, M., Haber, D. A., & Settleman, J. (2006). A common signaling cascade may underlie “addiction” to the Src, BCR-ABL, and EGF receptor oncogenes. Cancer Cell, 10(5), 425-435. https://doi.org/10.1016/j.ccr.2006.09.014

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