Construct · 1 fields · 1 citations

outside-inside hypothesis: a standalone construct

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Dermatology

the hypothesis that a primary skin barrier defect lets allergens in and drives the immune changes of atopic dermatitis, which then worsen the barrier.

In dermatology, outside-inside hypothesis refers to the hypothesis that a primary skin barrier defect lets allergens in and drives the immune changes of atopic dermatitis, which then worsen the barrier. This meaning comes from Elias (2008) in Journal of Allergy and Clinical Immunology.[1]

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Nearby constructs

barrier4 fields · 7 citationsjingle · one word, four constructs defect4 fields · 7 citationsjingle · one word, four constructs hypothesis2 fields · 2 citationsjingle · one word, two constructs

References

Elias, P. M., Hatano, Y., & Williams, M. L. (2008). Basis for the barrier abnormality in atopic dermatitis: Outside-inside-outside pathogenic mechanisms. Journal of Allergy and Clinical Immunology, 121(6), 1337-1343. https://doi.org/10.1016/j.jaci.2008.01.022

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