Construct · 1 fields · 1 citations

pathway-related uncertainty factor: a standalone construct

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Toxicology

an uncertainty factor for human toxicokinetic variability set from data on the specific metabolic pathway that clears a chemical, replacing the default.

In toxicology, pathway-related uncertainty factor refers to an uncertainty factor for human toxicokinetic variability set from data on the specific metabolic pathway that clears a chemical, replacing the default. This meaning comes from Dorne (2005) in Food and Chemical Toxicology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

default3 fields · 3 citationsjingle · one word, three constructs factor3 fields · 4 citationsjingle · one word, three constructs uncertainty factor1 fields · 1 citationsanchor · a standalone construct

References

Dorne, J. L. C. M., Walton, K., & Renwick, A. G. (2005). Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review. Food and Chemical Toxicology, 43(2), 203-216. https://doi.org/10.1016/j.fct.2004.05.011

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