Construct · 1 fields · 1 citations

pharmacophore: a standalone construct

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Pharmacology

the spatial arrangement of steric and electronic features a molecule needs to interact with a given biological target and trigger or block its response.

In pharmacology, pharmacophore refers to the spatial arrangement of steric and electronic features a molecule needs to interact with a given biological target and trigger or block its response. This meaning comes from Yang (2010) in Drug Discovery Today.[1]

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Nearby constructs

arrangement3 fields · 6 citationsjingle · one word, three constructs block3 fields · 6 citationsjingle · one word, three constructs response4 fields · 4 citationsjingle · one word, four constructs

References

Yang, S. (2010). Pharmacophore modeling and applications in drug discovery: challenges and recent advances. Drug Discovery Today, 15(11-12), 444-450. https://doi.org/10.1016/j.drudis.2010.03.013

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