Construct · 1 fields · 1 citations

phenotypic drug discovery: a standalone construct

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phenotypicdrug discovery1 CONSTRUCTPhenotypic drugSWINNEY · MEDICINAL CHEMISTRY

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Medicinal chemistry

discovery approach that selects compounds by their effect on a cell or organism phenotype without first fixing a molecular target.

In medicinal chemistry, phenotypic drug discovery refers to discovery approach that selects compounds by their effect on a cell or organism phenotype without first fixing a molecular target. This meaning comes from Swinney (2011) in Nature Reviews Drug Discovery.[1]

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructsphenotype4 fields · 4 citationsjingle · one word, four constructstarget4 fields · 6 citationsjingle · one word, four constructs

References

  1. Swinney, D. C., & Anthony, J. (2011). How were new medicines discovered? Nature Reviews Drug Discovery, 10(7), 507-519. https://doi.org/10.1038/nrd3480

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