Construct · 1 fields · 1 citations

phi-value analysis: a standalone construct

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Biophysics

a method that compares how mutations change folding kinetics and stability to map how far each residue's native contacts form in the transition state.

In biophysics, phi-value analysis refers to a method that compares how mutations change folding kinetics and stability to map how far each residue's native contacts form in the transition state. This meaning comes from Matouschek (1989) in Nature.[1]

Unit
Recovery means
Measured by

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Nearby constructs

form4 fields · 7 citationsjingle · one word, four constructs residue3 fields · 5 citationsjingle · one word, three constructs stability4 fields · 5 citationsjingle · one word, four constructs

References

Matouschek, A., Kellis, J. T., Serrano, L., & Fersht, A. R. (1989). Mapping the transition state and pathway of protein folding by protein engineering. Nature, 340(6229), 122-126. https://doi.org/10.1038/340122a0

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