Construct · 1 fields · 1 citations

probe dependence: a standalone construct

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Pharmacology

the finding that an allosteric modulator's effect on a receptor depends on which orthosteric ligand is used to probe it.

In pharmacology, probe dependence refers to the finding that an allosteric modulator's effect on a receptor depends on which orthosteric ligand is used to probe it. This meaning comes from May (2007) in Annual Review of Pharmacology and Toxicology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

dependence4 fields · 5 citationsjingle · one word, four constructs ligand2 fields · 2 citationsinvariant · one construct, two systems probe3 fields · 3 citationsjingle · one word, three constructs

References

May, L. T., Leach, K., Sexton, P. M., & Christopoulos, A. (2007). Allosteric Modulation of G Protein–Coupled Receptors. Annual Review of Pharmacology and Toxicology, 47(1), 1-51. https://doi.org/10.1146/annurev.pharmtox.47.120505.105159

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