Construct · 1 fields · 1 citations

protein binding displacement interaction: a standalone construct

One name. One construct. A landmark on the map.

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protein bindingdisplacement interaction1 CONSTRUCTProtein bindingBENET · PHARMACOKINETICS

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Pharmacokinetics

interaction in which one drug displaces another from plasma proteins, argued to have little clinical relevance because unbound exposure soon re-equilibrates.

In pharmacokinetics, protein binding displacement interaction refers to interaction in which one drug displaces another from plasma proteins, argued to have little clinical relevance because unbound exposure soon re-equilibrates. This meaning comes from Benet (2002) in Clinical Pharmacology & Therapeutics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

binding4 fields · 4 citationsjingle · one word, four constructsdisplacement5 fields · 6 citationsjingle · one word, five constructsexposure6 fields · 13 citationsjingle · one name, six constructs

References

  1. Benet, L. Z., & Hoener, B. (2002). Changes in plasma protein binding have little clinical relevance. Clinical Pharmacology & Therapeutics, 71(3), 115-121. https://doi.org/10.1067/mcp.2002.121829

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