Construct · 1 fields · 1 citations

punctuated evolution of cancer: a standalone construct

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Oncology

the finding that many tumor copy number changes arise in short bursts early in development followed by long periods of clonal stasis.

In oncology, punctuated evolution of cancer refers to the finding that many tumor copy number changes arise in short bursts early in development followed by long periods of clonal stasis. This meaning comes from Gao (2016) in Nature Genetics.[1]

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Nearby constructs

development1 fields · 2 citationsanchor · a standalone construct number3 fields · 6 citationsjingle · one word, three constructs short3 fields · 4 citationsjingle · one word, three constructs

References

Gao, R., Davis, A., McDonald, T. O., Sei, E., Shi, X., Wang, Y., Tsai, P., Casasent, A., Waters, J., Zhang, H., Meric-Bernstam, F., Michor, F., & Navin, N. E. (2016). Punctuated copy number evolution and clonal stasis in triple-negative breast cancer. Nature Genetics, 48(10), 1119-1130. https://doi.org/10.1038/ng.3641

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