Construct · 1 fields · 1 citations

reversible self-association of antibodies: a standalone construct

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Biopharmaceutical development

weak clustering of antibody molecules at high concentration that raises solution viscosity without permanent aggregation.

In biopharmaceutical development, reversible self-association of antibodies refers to weak clustering of antibody molecules at high concentration that raises solution viscosity without permanent aggregation. This meaning comes from Liu (2005) in Journal of Pharmaceutical Sciences.[1]

Unit
Recovery means
Measured by

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Nearby constructs

concentration4 fields · 4 citationsjingle · one word, four constructs development1 fields · 2 citationsanchor · a standalone construct solution3 fields · 4 citationsjingle · one word, three constructs

References

Liu, J., Nguyen, M. D. H., Andya, J. D., & Shire, S. J. (2005). Reversible Self-Association Increases the Viscosity of a Concentrated Monoclonal Antibody in Aqueous Solution. Journal of Pharmaceutical Sciences, 94(9), 1928-1940. https://doi.org/10.1002/jps.20347

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