Construct · 1 fields · 1 citations

target deconvolution: a standalone construct

One name. One construct. A landmark on the map.

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targetdeconvolution1 CONSTRUCTTarget deconvolutionTERSTAPPEN · DRUG DISCOVERY

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Drug discovery

identification of the molecular target or targets responsible for a compound's effect after a phenotypic screen.

In drug discovery, target deconvolution refers to identification of the molecular target or targets responsible for a compound's effect after a phenotypic screen. This meaning comes from Terstappen (2007) in Nature Reviews Drug Discovery.[1]

Unit
Recovery means
Measured by

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Nearby constructs

compound3 fields · 3 citationsjingle · one word, three constructsidentification6 fields · 9 citationsjingle · one word, six constructstarget4 fields · 6 citationsjingle · one word, four constructs

References

  1. Terstappen, G. C., Schlüpen, C., Raggiaschi, R., & Gaviraghi, G. (2007). Target deconvolution strategies in drug discovery. Nature Reviews Drug Discovery, 6(11), 891-903. https://doi.org/10.1038/nrd2410

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