Construct · 1 fields · 1 citations

thermodynamic signature: a standalone construct

One name. One construct. A landmark on the map.

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Drug discovery

the split of a drug's binding free energy into enthalpic and entropic parts, proposed to distinguish best-in-class compounds from earlier ones.

In drug discovery, thermodynamic signature refers to the split of a drug's binding free energy into enthalpic and entropic parts, proposed to distinguish best-in-class compounds from earlier ones. This meaning comes from Freire (2008) in Drug Discovery Today.[1]

Unit
Recovery means
Measured by

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Nearby constructs

binding4 fields · 4 citationsjingle · one word, four constructs energy5 fields · 10 citationsjingle · one word, five constructs free energy3 fields · 7 citationsjingle · one word, three constructs

References

Freire, E. (2008). Do enthalpy and entropy distinguish first in class from best in class? Drug Discovery Today, 13(19-20), 869-874. https://doi.org/10.1016/j.drudis.2008.07.005

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