Construct · 1 fields · 1 citations

thymic selection: a standalone construct

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Immunology

the sorting of developing T cells by self-peptide recognition, keeping useful specificities and deleting dangerous ones.

In immunology, thymic selection refers to the sorting of developing T cells by self-peptide recognition, keeping useful specificities and deleting dangerous ones. This meaning comes from Kisielow (1988) in Nature.[1]

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Nearby constructs

recognition4 fields · 5 citationsjingle · one word, four constructs selection4 fields · 5 citationsjingle · one word, four constructs sorting4 fields · 6 citationsjingle · one word, four constructs

References

Kisielow, P., Blüthmann, H., Staerz, U. D., Steinmetz, M., & von Boehmer, H. (1988). Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes. Nature, 333(6175), 742-746. https://doi.org/10.1038/333742a0

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