Construct · 1 fields · 1 citations

transcription-coupled repair: a standalone construct

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Molecular biology

preferential removal of lesions from the transcribed strand of active genes, triggered by a stalled polymerase.

In molecular biology, transcription-coupled repair refers to preferential removal of lesions from the transcribed strand of active genes, triggered by a stalled polymerase. This meaning comes from Mellon (1987) in Cell.[1]

Unit
Recovery means
Measured by

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructs polymerase1 fields · 1 citationsanchor · a single construct strand1 fields · 1 citationsanchor · a standalone construct

References

Mellon, I. (1987). Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene. Cell, 51(2), 241-249. https://doi.org/10.1016/0092-8674(87)90151-6

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