Construct · 1 fields · 1 citations

transcriptomic point of departure: a standalone construct

One name. One construct. A landmark on the map.

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transcriptomicpoint of departure1 CONSTRUCTTranscriptomic point ofTHOMAS · TOXICOLOGY

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Toxicology

a dose at which gene expression changes in a tissue begin, found to track the dose of apical toxic effects in animal studies.

In toxicology, transcriptomic point of departure refers to a dose at which gene expression changes in a tissue begin, found to track the dose of apical toxic effects in animal studies. This meaning comes from Thomas (2013) in Toxicological Sciences.[1]

Unit
Recovery means
Measured by

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Nearby constructs

dose3 fields · 3 citationsinvariant · one construct, three systemsexpression4 fields · 4 citationsjingle · one word, four constructs

References

  1. Thomas, R. S., Wesselkamper, S. C., Wang, N. C. Y., Zhao, Q. J., Petersen, D. D., Lambert, J. C., Cote, I., Yang, L., Healy, E., Black, M. B., Clewell, H. J., Allen, B. C., & Andersen, M. E. (2013). Temporal Concordance Between Apical and Transcriptional Points of Departure for Chemical Risk Assessment. Toxicological Sciences, 134(1), 180-194. https://doi.org/10.1093/toxsci/kft094

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