Construct · 1 fields · 1 citations

transduction coefficient: a standalone construct

One name. One construct. A landmark on the map.

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Pharmacology

single parameter combining agonist efficacy and affinity, log(tau/KA), used to quantify and compare agonist bias between signaling pathways.

In pharmacology, transduction coefficient refers to single parameter combining agonist efficacy and affinity, log(tau/KA), used to quantify and compare agonist bias between signaling pathways. This meaning comes from Kenakin (2012) in ACS Chemical Neuroscience.[1]

Unit
Recovery means
Measured by

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Nearby constructs

affinity3 fields · 4 citationsjingle · one word, three constructs agonist1 fields · 3 citationsanchor · a standalone construct bias6 fields · 8 citationsjingle · one name, six constructs

References

Kenakin, T., Watson, C., Muniz-Medina, V., Christopoulos, A., & Novick, S. (2012). A Simple Method for Quantifying Functional Selectivity and Agonist Bias. ACS Chemical Neuroscience, 3(3), 193-203. https://doi.org/10.1021/cn200111m

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