Construct · 1 fields · 1 citations

tumor mutational burden: a standalone construct

One name. One construct. A landmark on the map.

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tumor mutationalburden1 CONSTRUCTTumor mutational burdenCHALMERS · CANCER BIOLOGY

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Cancer biology

the number of somatic mutations per megabase of tumor genome, used as a marker of likely response to immunotherapy.

In cancer biology, tumor mutational burden refers to the number of somatic mutations per megabase of tumor genome, used as a marker of likely response to immunotherapy. This meaning comes from Chalmers (2017) in Genome Medicine.[1]

Unit
Recovery means
Measured by

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Nearby constructs

burden3 fields · 6 citationsjingle · one word, three constructsmarker3 fields · 5 citationsjingle · one word, three constructsnumber3 fields · 6 citationsjingle · one word, three constructs

References

  1. Chalmers, Z. R., Connelly, C. F., Fabrizio, D., Gay, L., Ali, S. M., Ennis, R., Schrock, A., Campbell, B., Shlien, A., Chmielecki, J., Huang, F., He, Y., Sun, J., Tabori, U., Kennedy, M., Lieber, D. S., Roels, S., White, J., Otto, G. A., Ross, J. S., Garraway, L., Miller, V. A., Stephens, P. J., & Frampton, G. M. (2017). Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden. Genome Medicine, 9(1). https://doi.org/10.1186/s13073-017-0424-2

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