Construct · 1 fields · 1 citations

zinc finger nuclease: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Genome editing

designed protein joining zinc finger DNA recognition to a FokI cutting domain to break DNA at a chosen site.

In genome editing, zinc finger nuclease refers to designed protein joining zinc finger DNA recognition to a FokI cutting domain to break DNA at a chosen site. This meaning comes from Kim (1996) in Proceedings of the National Academy of Sciences.[1]

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Nearby constructs

break2 fields · 4 citationsjingle · one word, two constructs domain3 fields · 4 citationsjingle · one word, three constructs editing1 fields · 2 citationsanchor · a standalone construct

References

Kim, Y. G., Cha, J., & Chandrasegaran, S. (1996). Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain. Proceedings of the National Academy of Sciences, 93(3), 1156-1160. https://doi.org/10.1073/pnas.93.3.1156

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