Construct · 1 fields · 1 citations

allosteric ternary complex model: a standalone construct

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Pharmacology

model of a receptor binding an orthosteric and an allosteric ligand at once, with a cooperativity factor describing how each changes the other's affinity.

In pharmacology, allosteric ternary complex model refers to model of a receptor binding an orthosteric and an allosteric ligand at once, with a cooperativity factor describing how each changes the other's affinity. This meaning comes from Christopoulos (2002) in Pharmacological Reviews.[1]

Unit
Recovery means
Measured by

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Nearby constructs

affinity3 fields · 4 citationsjingle · one word, three constructs binding4 fields · 4 citationsjingle · one word, four constructs complex4 fields · 4 citationsjingle · one word, four constructs

References

Christopoulos, A., & Kenakin, T. (2002). G Protein-Coupled Receptor Allosterism and Complexing. Pharmacological Reviews, 54(2), 323-374. https://doi.org/10.1124/pr.54.2.323

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