Construct · 1 fields · 1 citations

ternary complex model: a standalone construct

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Pharmacology

receptor model in which an agonist, its receptor and a G protein form a high-affinity three-part complex that explains agonist-specific binding behavior.

In pharmacology, ternary complex model refers to receptor model in which an agonist, its receptor and a G protein form a high-affinity three-part complex that explains agonist-specific binding behavior. This meaning comes from De Lean (1980) in Journal of Biological Chemistry.[1]

Unit
Recovery means
Measured by

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Nearby constructs

agonist1 fields · 3 citationsanchor · a standalone construct allosteric ternary complex model1 fields · 1 citationsanchor · a standalone construct binding4 fields · 4 citationsjingle · one word, four constructs

References

De Lean, A., Stadel, J. M., & Lefkowitz, R. J. (1980). A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor. Journal of Biological Chemistry, 255(15), 7108-7117. https://doi.org/10.1016/s0021-9258(20)79672-9

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