Construct · 2 fields · 2 citations

Where does cap collide?

One name. Different field. Different construct. One map.

● jingle · one word, two constructs Nearest construct by meaning·not indexed
cap2 CONSTRUCTSmRNA capSHATKIN · 5' mRNAPrice capBEESLEY · RPI−X

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1976mRNA cap1989Price cap
2026

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Molecular biology

A protective tag added to a messenger RNA's 5' end

In molecular biology the cap is a modified guanine nucleotide, 7-methylguanosine, joined through an unusual 5'-to-5' triphosphate linkage to the start of a eukaryotic messenger RNA soon after transcription begins. It protects the transcript from degradation by exonucleases and is recognised by the translation machinery, so an uncapped message is neither stable nor efficiently read. Shatkin's 1976 Capping of eucaryotic mRNAs drew together the early evidence for this structure and its function. The referent is a chemical tag on a nucleic acid, sharing nothing with a floating mat of grape skins or a ceiling on prices beyond the word.[1]

Unit
Presence and structure of the 5' 7-methylguanosine tag on a transcript
Recovery means
Not applicable
Measured by
Detected by cap-specific labelling, resistance to 5' exonucleases, and binding of cap-recognition proteins

Regulatory economics

A regulated ceiling on the prices a monopoly may charge

In regulatory economics a price cap is a ceiling a regulator places on the prices a dominant firm may charge, typically allowing increases only up to inflation minus an efficiency factor, so the firm keeps the gains from cutting its own costs. Beesley and Littlechild's 1989 The regulation of privatized monopolies in the United Kingdom set out the logic of this RPI−X approach as an alternative to regulating a firm's rate of return. The referent is a policy instrument constraining prices, measured by the permitted price path, and it is unrelated to a molecular tag or a layer of grape solids.[2]

Unit
The maximum allowed price or price path set by a regulator
Recovery means
Not applicable
Measured by
Expressed as a permitted price-change formula (e.g. RPI minus an efficiency factor X) and monitored against actual charges

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Nearby collisions

ceiling4 fields · 8 citationsjingle · one word, four constructsbusiness1 fields · 1 citationsanchor · a standalone constructcarry1 fields · 1 citationsanchor · a standalone construct

References

  1. Shatkin, A. J. (1976). Capping of eucaryotic mRNAs. Cell, 9(4), 645–653. https://doi.org/10.1016/0092-8674(76)90128-8
  2. Beesley, M. E., & Littlechild, S. C. (1989). The regulation of privatized monopolies in the United Kingdom. The RAND Journal of Economics, 20(3), 454–472. https://doi.org/10.2307/2555582

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