Construct · 1 fields · 1 citations

Cas12a: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Genome editing

class 2 CRISPR nuclease using one short CRISPR RNA and leaving staggered cuts at T-rich target sites.

In genome editing, Cas12a refers to class 2 CRISPR nuclease using one short CRISPR RNA and leaving staggered cuts at T-rich target sites. This meaning comes from Zetsche (2015) in Cell.[1]

Unit
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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructs class3 fields · 3 citationsjingle · one word, three constructs editing1 fields · 2 citationsanchor · a standalone construct

References

Zetsche, B., Gootenberg, J. S., Abudayyeh, O. O., Slaymaker, I. M., Makarova, K. S., Essletzbichler, P., Volz, S. E., Joung, J., van der Oost, J., Regev, A., Koonin, E. V., & Zhang, F. (2015). Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System. Cell, 163(3), 759-771. https://doi.org/10.1016/j.cell.2015.09.038

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