Construct · 1 fields · 1 citations

cassette: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed
cassette1 CONSTRUCTGene cassetteSTOKES & HALL · 1989

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Molecular genetics

A mobile, swappable package of a gene

In molecular genetics, a gene cassette is a small mobile DNA unit, typically a single gene plus a site-specific recombination site, that can be captured into or excised from a larger element called an integron and shuffled between genomes, which is how many bacteria rapidly acquire new antibiotic-resistance genes. Stokes and Hall's 1989 A novel family of potentially mobile DNA elements encoding site-specific gene-integration functions: Integrons first described the integron and the cassettes it collects. The referent is a discrete, interchangeable genetic module defined by its mobility and recombination site, sharing with a bike part and a tape only the idea of a self-contained package that slots in and out.[1]

Unit
The discrete gene-plus-recombination-site module that integrates or excises
Recovery means
Not applicable
Measured by
Identified by sequencing the cassette's gene and its attC recombination site and its position within an integron array

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Nearby constructs

body2 fields · 3 citationsjingle · one word, two constructscadence3 fields · 3 citationsjingle · one word, three constructschain3 fields · 3 citationsjingle · one word, three constructs

References

  1. Stokes, H. W., & Hall, R. M. (1989). A novel family of potentially mobile DNA elements encoding site-specific gene-integration functions: Integrons. Molecular Microbiology, 3(12), 1669–1683. https://doi.org/10.1111/j.1365-2958.1989.tb00153.x

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