Construct · 1 fields · 1 citations

clonal evolution of tumors: a standalone construct

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Cancer biology

the view that tumors progress by successive mutation and selection of increasingly aggressive cell clones.

In cancer biology, clonal evolution of tumors refers to the view that tumors progress by successive mutation and selection of increasingly aggressive cell clones. This meaning comes from Nowell (1976) in Science.[1]

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Nearby constructs

progression3 fields · 6 citationsjingle · one word, three constructs cell2 fields · 3 citationsjingle · one word, two constructs mutation4 fields · 4 citationsjingle · one word, four constructs

References

Nowell, P. C. (1976). The Clonal Evolution of Tumor Cell Populations: Acquired genetic lability permits stepwise selection of variant sublines and underlies tumor progression. Science, 194(4260), 23-28. https://doi.org/10.1126/science.959840

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