Construct · 1 fields · 1 citations

CRISPR-based nucleic acid detection: a standalone construct

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CRISPR-based nucleicacid detection1 CONSTRUCTCRISPR-based nucleicGOOTENBERG · BIOTECHNOLOGY

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Biotechnology

diagnostic format in which a guide-directed CRISPR nuclease cleaves a reporter once its target sequence is present.

In biotechnology, CRISPR-based nucleic acid detection refers to diagnostic format in which a guide-directed CRISPR nuclease cleaves a reporter once its target sequence is present. This meaning comes from Gootenberg (2017) in Science.[1]

Unit
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Measured by

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Nearby constructs

SHERLOCK detection1 fields · 1 citationsanchor · a standalone constructacid2 fields · 2 citationsjingle · one word, two carrierssequence3 fields · 3 citationsjingle · one word, three constructs

References

  1. Gootenberg, J. S., Abudayyeh, O. O., Lee, J. W., Essletzbichler, P., Dy, A. J., Joung, J., Verdine, V., Donghia, N., Daringer, N. M., Freije, C. A., Myhrvold, C., Bhattacharyya, R. P., Livny, J., Regev, A., Koonin, E. V., Hung, D. T., Sabeti, P. C., Collins, J. J., & Zhang, F. (2017). Nucleic acid detection with CRISPR-Cas13a/C2c2. Science, 356(6336), 438-442. https://doi.org/10.1126/science.aam9321

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