Construct · 1 fields · 1 citations

SHERLOCK detection: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed
SHERLOCKdetection1 CONSTRUCTSHERLOCK detectionGOOTENBERG · DIAGNOSTICS

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Diagnostics

nucleic acid test where target recognition by Cas13 sets off cutting of reporter RNA, giving an amplified readout.

In diagnostics, SHERLOCK detection refers to nucleic acid test where target recognition by Cas13 sets off cutting of reporter RNA, giving an amplified readout. This meaning comes from Gootenberg (2017) in Science.[1]

Unit
Recovery means
Measured by

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Nearby constructs

CRISPR-based nucleic acid detection1 fields · 1 citationsanchor · a standalone constructacid2 fields · 2 citationsjingle · one word, two carriersCas131 fields · 1 citationsanchor · a standalone construct

References

  1. Gootenberg, J. S., Abudayyeh, O. O., Lee, J. W., Essletzbichler, P., Dy, A. J., Joung, J., Verdine, V., Donghia, N., Daringer, N. M., Freije, C. A., Myhrvold, C., Bhattacharyya, R. P., Livny, J., Regev, A., Koonin, E. V., Hung, D. T., Sabeti, P. C., Collins, J. J., & Zhang, F. (2017). Nucleic acid detection with CRISPR-Cas13a/C2c2. Science, 356(6336), 438-442. https://doi.org/10.1126/science.aam9321

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